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Computer support of DNA sequence analysis

✍ Scribed by G Osterburg; R Sommer

Publisher
Elsevier Science
Year
1981
Weight
562 KB
Volume
13
Category
Article
ISSN
0010-468X

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✦ Synopsis

The paper describes a package of APL-programs suited for the management and the analysis of DNA sequence data. Most of the application programs are related to experimental work in a DNA sequencing laboratory: Search for overlapping DNA fragments to construct complete DNA sequences; search for restriction sites; computing fragment patterns when cutting a DNA with restriction enzymes; plotting physical and genetic maps of a DNA; search for homologies as well as various counting procedures. More sophisticated programs are concerned with the prediction of RNA secondary structure and its graphical representation.

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