One hundred hypothetical polynucleotides of varying chain length and composition and of random sequence were generated and their chemical degradation simulated by a computer. Included in the study were 20 hypothetical polymers with the composition and chain length of a transfer RNA. A second compute
Computer program for storage and retrieval of the nucleic acid structures: Storing and updating of transfer RNA sequences — Drawing of the secondary structure for transfer RNA by computer
✍ Scribed by Ram P. Singhal; Robert C. Ray; Larry Dobbs
- Publisher
- Elsevier Science
- Year
- 1982
- Weight
- 410 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0010-468X
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✦ Synopsis
The availability of a large nur~tber of tRNA sequences has created a need for computer programs to store the data. A program written in FORTRAN language allows one to store tRNA sequences and to retrieve information. The data are stored in such a way that it allows a direct comparison of various tRNA sequences. Moreover, the program draws the "cloverleaf' structure of any stored tRNA sequence and also provides the characteris~.ics of minor, modified nucleosides and major references. Additions and corrections to the program and stored data can be made easily and an individual does not need computer programming skills to use the program.
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