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Computer Modeling of the Solution Conformation of Cyclic Enkephalins

✍ Scribed by Joanna Malicka; Małgorzata Groth; Cezary Czaplewski; Regina Kasprzykowska; Adam Liwo; Leszek Łankiewicz; Wieslaw Wiczk

Book ID
110269345
Publisher
Springer Netherlands
Year
1998
Tongue
English
Weight
484 KB
Volume
5
Category
Article
ISSN
1573-3149

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Conformational studies of diastereomeric
Conformational studies of diastereomeric cyclic enkephalins by 1H-NMR and computer simulations
✍ Dale F. Mierke; Pierluigi Lucietto; Murray Goodman; Peter W. Schiller 📂 Article 📅 1987 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 772 KB

## Synopsis We report the solid-phase synthesis and conformational analysis of a 14-membered, cyclic enkephalin analog, H-Tyr-~$-~-A,bu-Gly-Phe-~-Leu-] (where A,bu represents a,ydiaminobutyric acid). The results from the guinea pig ileum (GPI) and mouse vas deferens (MVD) assays show that the anal