Computer methodology for simulation and prediction of alloimmune responses: Expected antibody specificities

✍ Scribed by J. Altarriba; I. Zarazaga; B. Amorena

• Publisher: Elsevier Science
• Year: 1983
• Tongue: English
• Weight: 641 KB
• Volume: 13
• Category: Article
• ISSN: 0010-4825
• DOI: 10.1016/0010-4825(83)90002-1

✦ Synopsis

The methodology presented here was developed for simulating planned alloimmunization results, with regard to the type and number ofexpected antibody specificities. The computer program designed for this purpose was adapted to an immunogenetic model using Boolean algebra. It was written to help immuno~neti~sts avoid hiding routine data preceding selection of donor-recipient pairs, specially concerning blood type alloi~unizations in animals: all of the donor-recipient combinations and the expected antibody specificities (their limit number being specified in each particular immunization program) are provided in the print-out.