Computer-assisted multifactor optimization of selectivity in gas chromatography
β Scribed by Q. S. Wang; C. S. Zhu; B. W. Yan; H. B. Chen
- Book ID
- 112722806
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 356 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0009-5893
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Three variables characterizing the mobile phase composition, pH, elution strength and ionic strength, have been studied in order to construct a three-dimensional semiempirical model for predicting retention times of dibasic substances. The solutes treated quantitatively include dibasic acids and bas
## Abstract A computerβassisted method is presented for optimization of mobile phase composition in reverseβphase and normalβphase HPLC. The method is based on window diagrams, but only three preliminary tests are required. The method is successfully applied to two examples and there is good agreem