Computer analysis of structure-activity relationship for selective and nonselective inhibitors of cyclooxygenases 1 and 2
✍ Scribed by V. R. Khairullina; A. D. Mukhametov; G. G. Garifullina; A. Ya. Gerchikov; L. A. Tyurina; F. S. Zarudii
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 99 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0091-150X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Objective To simultaneously assess the short‐term reduction in risk of gastrointestinal (GI) complications and increase in risk of acute myocardial infarction (MI) by celecoxib compared with rofecoxib and several nonselective nonsteroidal antiinflammatory drugs (NSAIDs) using instru
## Abstract Structure‐based quantitative structure‐activity relationship (QSAR) studies on a series of checkpoint kinase 1 (Chk1) inhibitors were performed to find the key structural features responsible for their inhibitory activity. Molecular docking was employed to explore the binding mode of al