Computer-Aided Organic Synthesis – SESAM: A Simple Program to Unravel “Hidden” Restructured Starting Materials Skeleta in Complex Targets

✍ Scribed by Goverdhan Mehta; René Barone; Michel Chanon

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 234 KB
• Volume: 1998
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/(sici)1099-0690(199807)1998:7<1409::aid-ejoc1409>3.0.co;2-h

✦ Synopsis

We describe the SESAM program whose aim is to help the and attempts to map simply modified starting materials into the skeletal surface of the target. SESAM has been tested on chemist in exploring new synthetic strategies for complex structures by locating simple, non-obvious but effective taxol and steroid frameworks. starting materials. The program works at the skeletal level