✦ LIBER ✦

Computer-Aided Design, Synthesis, and Anti-HIV-1 Activity in Vitro of 2-Alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3 H )- ones as Novel Potent Non-Nucleoside Reverse Transcriptase Inhibitors, Also Active Against the Y181C Variant

✍ Scribed by Ragno, Rino; Mai, Antonello; Sbardella, Gianluca; Artico, Marino; Massa, Silvio; Musiu, Chiara; Mura, Massimo; Marturana, Flavia; Cadeddu, Alessandra; La Colla, Paolo

Book ID: 118158680
Publisher: American Chemical Society
Year: 2004
Tongue: English
Weight: 245 KB
Volume: 47
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm0309856

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Structure-Based Design, Synthesis, and B

Structure-Based Design, Synthesis, and Biological Evaluation of Conformationally Restricted Novel 2-Alkylthio-6-[1-(2,6-difluorophenyl)alkyl]- 3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase

✍ Mai, Antonello; Sbardella, Gianluca; Artico, Marino; Ragno, Rino; Massa, Silvio; 📂 Article 📅 2001 🏛 American Chemical Society 🌐 English ⚖ 238 KB

Synthesis and Anti-HIV-1 Activity Evalua

Synthesis and Anti-HIV-1 Activity Evaluation of 5-Alkyl-2-alkylthio-6-(arylcarbonyl or α-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as Novel Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors.

✍ Ji, Lei; Chen, Fen-Er; De Clercq, Erik; Balzarini, Jan; Pannecouque, Christophe 📂 Article 📅 2007 🏛 American Chemical Society 🌐 English ⚖ 8 KB

Synthesis and Anti-HIV-1 Activity Evalua

✍ Ji, Lei; Chen, Fen-Er; De Clercq, Erik; Balzarini, Jan; Pannecouque, Christophe 📂 Article 📅 2007 🏛 American Chemical Society 🌐 English ⚖ 209 KB

Non-Nucleoside HIV-1 Reverse-Transcripta

Non-Nucleoside HIV-1 Reverse-Transcriptase Inhibitors. Part 10 : Synthesis and Anti-HIV Activity of 5-Alkyl-6-(1-naphthylmethyl)pyrimidin-4(3H)-ones with a Mono- or Disubstituted 2-Amino Function as Novel ‘Dihydro-Alkoxy-Benzyl-Oxopyrimidine’ (DABO) Analogues

✍ Yueping Wang; Fen-Er Chen; Jan Balzarini; Erik De Clercq; Christophe Pannecouque 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 227 KB 👁 2 views