Malaria, a life-threatening disease caused by parasites of the genus Plasmodium, affects 500 million people annually, of which more than one million die. [1] The emergence of multi-drugresistant strains of Plasmodium falciparum, the parasite that causes the deadliest form of malaria, exacerbates the
Computer-Aided Design and Synthesis of Nonpeptidic Plasmepsin II and IV Inhibitors
✍ Scribed by Torsten Luksch; Nan-Si Chan; Sascha Brass; Christoph A. Sotriffer; Gerhard Klebe; Wibke E. Diederich
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 825 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1860-7179
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Plasmodium species are the causative agents of malaria, infecting 300-660 million people annually and killing 1-2 million. Malaria is undisputedly a disease of poverty and suffers from a lack of business-driven drug research, therefore requiring new initiatives to overcome this absence of market in
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