Computer aided analysis for biosensing and screening
โ Scribed by Xiang-Ming Li; Bernard S. Liang; Henry Y. Wang
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 548 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0006-3592
No coin nor oath required. For personal study only.
โฆ Synopsis
Biosensors with animal and microbial cells immobilized close t o the tip of a membrane electrode hsve been developed for chemical and drug testing. Our experimental results show that biosensors can be used for drug screening and to provide useful information about various cell-chemical interactions. A computer aided analysis (CAA) software package is being developed here using the biosensor for various screening purposes. This software package enables us to use a computer t o analyze the biosensor dynamic responses. Computer simulation and parameter estimation techniques are used to select the best model and to describe the biochemical and pharmacologic effects of various chemicals and drugs on different cell lines.
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