the fourteenth hospital day. During days 7 to 14, the patient continued in normal sinus rhythm without any bradyrhythmias or tachyrhythmias. Blood pressure remained stable at approximately 140/80 without marked fluctuation. Respirations remained between 18 and 20, and forced vital capacity increased
Computed tomography in the diagnosis of Canavan's disease
β Scribed by Alan R. Rushton; Dr. Bennett A. Shaywitz; Charles C. Duncan; Robert B. Geehr; Elias E. Manuelidis
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 486 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Computed tomography (CT scan) demonstrated a symmetrical decrease in white matter attenuation of the cerebral hemispheres of two young children with macrocephaly and normal neurological examination. Subsequent developmental delay led to brain biopsy, which documented Canavan's disease (spongy degeneration of the brain, Van BogaertβBertrand type). The CT scans obtained from these patients with proved Canavan's disease appeared to be quite characteristic in differentiating this disorder from Alexander's disease and adrenoleukodystrophy (Schilder's disease). The CT scan may decrease the necessity for diagnostic brain biopsy in these white matter disorders.
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We present the first report on the use of helical computed tomography (CT), a new, non-invasive diagnostic technique that produces three-dimensional (3-D) images, in prenatal diagnosis. This technique was used to construct 3-D images in the prenatal diagnosis of two anomalous fetuses. The 3-D images