Computed tomography in acute left colonic diverticulitis

✍ Scribed by M. Huguier; P. Ambrosetti

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 137 KB
• Volume: 84
• Category: Article
• ISSN: 0007-1323
• DOI: 10.1002/bjs.1800841043

✦ Synopsis

blood flow and increase the tubular production of urine by its diuretic action but the only prospective trial to assess its effect in jaundiced patients failed to demonstrate any significant benefit and showed that postoperative deterioration in renal function was actually greater in patients receiving mannitoP. The routine use of mannitol in this setting is not effective and may even be detrimental if it exacerbates pre-existing hypovolaemia and hypotension due to its osmotic potential.

Clearly, further studies on the systemic and renal haemodynamics of obstructive jaundice are required. At present, we suggest caution in the routine perioperative use of mannitol in jaundiced patients as it may initially improve urine output but ultimately do harm and precipitate renal impairment.