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Computed tomography brain changes in Parkinsonian dementia

✍ Scribed by R. Inzelberg; T. Treves; I. Reider; I. Gerlenter; A. D. Korczyn

Publisher: Springer
Year: 1987
Tongue: English
Weight: 456 KB
Volume: 29
Category: Article
ISSN: 0028-3940
DOI: 10.1007/bf00350436

No coin nor oath required. For personal study only.

✦ Synopsis

In order to evaluate the relationship between brain atrophy and the motor and cognitive function in Parkinson's disease, we have evaluated CT changes in 132 consecutive patients and compared them to measures of physical and mental decline, using intercorrelations and variance analysis. The result demonstrated age as a most important factor relating to brain atrophy. After correction for this determinant, it became clear that the motor and cognitive parameters were interdependent but they affected similar CT parameters. The effect of motor decline was the stronger of the two and it was the only one which correlated with cortical atrophy. The results support the notion of subcortical changes underlying the dementia of Parkinson's disease.

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