Computationally Efficient Multipoint Linkage Analysis on Extended Pedigrees for Trait Models With Two Contributing Major Loci

MCMC-based linkage analysis for complex

MCMC-based linkage analysis for complex traits on general pedigrees: multipoint analysis with a two-locus model and a polygenic component

✍ Yun Ju Sung; Elizabeth A. Thompson; Ellen M. Wijsman 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 283 KB 👁 1 views

## Abstract We describe a new program lm\_twoqtl, part of the MORGAN package, for parametric linkage analysis with a quantitative trait locus (QTL) model having one or two QTLs and a polygenic component, which models additional familial correlation from other unlinked QTLs. The program has no restr