Computationally efficient dynamic modelling and simulation of simulated moving bed chromatographic processes with linear isotherms

✍ Scribed by G. Dünnebier; I. Weirich; K.-U. Klatt

• Publisher: Elsevier Science
• Year: 1998
• Tongue: English
• Weight: 283 KB
• Volume: 53
• Category: Article
• ISSN: 0009-2509
• DOI: 10.1016/s0009-2509(98)00076-1

✦ Synopsis

This paper presents a new approach for the dynamic simulation of linear chromatographic processes, in particular, for the simulated moving bed (SMB) process. The goal of this work was the development of a computationally efficient model which is needed for modelbased process control. Three different modelling and simulation approaches are presented and compared: an analytical solution of the equilibrium model, a closed-form solution of model equations considering both axial dispersion and mass transfer resistance, and a numerical solution of the general rate model. The solutions are compared with respect to complexity, accuracy and computation time. The new developed closed-form solution gives a high accuracy with low computations time.