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Computational Study of the Thermodynamics and Stability of Two Trp-Cage Miniprotein Sequences

✍ Scribed by English, Charles A.; Garcia, Angel E.

Book ID
122193655
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
69 KB
Volume
102
Category
Article
ISSN
0006-3495

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✍ Jeffrey Copps; Richard F. Murphy; SΓ‘ndor Lovas πŸ“‚ Article πŸ“… 2007 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 661 KB

## Abstract TC5b is a 20 residue polypeptide notable for its compact tertiary structure, a rarity for a short peptide. This structure is due to the β€œTrp‐cageβ€œ motif, an association of aromatic, Pro, and Gly residues. The structure of TC5b has been fully characterized by NMR and electronic circular