A pharmacokinetic study of the dopamine 0 2 receptor agonist ( S)-(-)-2-(Npropyl-N(2-thienylethyl)amino)-5-hydroxytetralimHCl (K0923) infused in female cynomolgus monkeys over a 4-h period was carried out at International Research and Development Corporation. The purpose of this study was to estimat
✦ LIBER ✦
Computational study of 2-aminopyrimidine, 2-amino-5-nitropyrimidine, and the corresponding S,S-dimethyl-N-sulfilimines
✍ Scribed by Politzer, Peter; Kirschenheuter, Gary P.; Miller, Richard S.
- Book ID
- 120385585
- Publisher
- American Chemical Society
- Year
- 1988
- Tongue
- English
- Weight
- 604 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0022-3654
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## Abstract The isomeric 2‐substituted‐7(5)‐methyl‐2,3‐dihydro‐5(7)__H__‐oxazolo[3,2‐__a__]pyrimidin‐5‐ones **3a‐b** and 7‐ones **2a‐b,7a** were synthesized by cyclocondensation from the 5‐substituted‐2‐amino‐2‐oxazolines **1a‐b** with biselectrophiles. In boiling ethanol, the reaction of **1a‐b**