NMR-Based Structural Studies of Damaged
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Hsiang Chuan Kung; Ke Yu Wang; Sharon A. Parker; Igor Goljer; Philip H. Bolton
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Article
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1996
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John Wiley and Sons
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English
β 690 KB
The structures of duplex DNAs containing damaged sites can be determined by the combined use of NMR and restrained molecular dynamics. The NMR of DNAs containing abasic sites can be challenging since there are two equilibrating forms of the abasic site present. The damaged sites also tend to have fe