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Computational studies of protein regulation by post-translational phosphorylation

✍ Scribed by Arjun Narayanan; Matthew P Jacobson

Book ID
113883245
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
611 KB
Volume
19
Category
Article
ISSN
0959-440X

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## Abstract Osteopontin (OPN) plays roles in a variety of cellular processes from bone resorption and extracellular matrix (ECM) remodeling to immune cell activation and inhibition of apoptosis. Because it binds receptors (integrins, CD44 variants) typically engaged by ECM molecules, OPN acts as a