Synthesis and preliminary evaluation of
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Daniel J. Canney; Yu-Zhi Guo; Mei-Ping Kung; Hank F. Kung
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Article
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1993
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John Wiley and Sons
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French
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## Abstract A derivative of tetrabenazine (TBZ, __1__) containing an iodovinyl group (IโTBZ, __3b__) was prepared as a potential radiotracer for the vesicular monoamine transporter. The synthesis of __3a__ was achieved by ethynylation of TBZ. The ethynyl derivative __4__, was converted to the corre