✦ LIBER ✦

Computational methods in protein structure prediction

✍ Scribed by C.A. Floudas

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 210 KB
Volume: 97
Category: Article
ISSN: 0006-3592
DOI: 10.1002/bit.21411

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

This review presents the advances in protein structure prediction from the computational methods perspective. The approaches are classified into four major categories: comparative modeling, fold recognition, first principles methods that employ database information, and first principles methods without database information. Important advances along with current limitations and challenges are presented. Biotechnol. Bioeng. 2007;97: 207–213. © 2007 Wiley Periodicals, Inc.

📜 SIMILAR VOLUMES

New methods for accurate prediction of p

New methods for accurate prediction of protein secondary structure

✍ John-Marc Chandonia; Martin Karplus 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 122 KB 👁 2 views

A primary and a secondary neural network are applied to secondary structure and structural class prediction for a database of 681 non-homologous protein chains. A new method of decoding the outputs of the secondary structure prediction network is used to produce an estimate of the probability of fin

Critical assessment of methods of protei

Critical assessment of methods of protein structure prediction (CASP): Round II

✍ Moult, John; Hubbard, Tim; Bryant, Stephen H.; Fidelis, Krzysztof; Pedersen, Jan 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 35 KB 👁 2 views

The point is that, whenever we propose a solution to a problem we ought to try as hard as we can to overthrow our solution, rather than defend it. Few of us, unfortunately, practice this percept; but other people, fortunately, will supply the criticism for us if we fail to supply it ourselves.

Critical assessment of methods of protei

Critical assessment of methods of protein structure prediction (CASP): Round III

✍ John Moult; Tim Hubbard; Krzysztof Fidelis; Jan T. Pedersen 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 61 KB 👁 2 views

Computational investigation of kinetics

Computational investigation of kinetics of cross-linking reactions in proteins: Importance in structure prediction

✍ Pradipta Bandyopadhyay; Irwin D. Kuntz 📂 Article 📅 2009 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 239 KB 👁 1 views

Biomolecular Structure Prediction Stocha

Biomolecular Structure Prediction Stochastic Optimization Methods

✍ A. Schug; B. Fischer; A. Verma; H. Merlitz; W. Wenzel; G. Schoen 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB 👁 1 views

Evaluation and improvement of multiple s

Evaluation and improvement of multiple sequence methods for protein secondary structure prediction

✍ James A. Cuff; Geoffrey J. Barton 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB 👁 2 views

A new dataset of 396 protein domains is developed and used to evaluate the performance of the protein secondary structure prediction algorithms DSC, PHD, NNSSP, and PREDATOR. The maximum theoretical Q 3 accuracy for combination of these methods is shown to be 78%. A simple consensus prediction on th