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Computational method to assign microbial genes to pathways

✍ Scribed by Matteo Pellegrini; Michael Thompson; Joseph Fierro; Peter Bowers

Book ID
102299552
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
205 KB
Volume
84
Category
Article
ISSN
0730-2312

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✦ Synopsis

We present techniques that mine fully sequenced microbial genomes for functional relationships between genes. We show that genes related by one of four techniques are more likely to belong to the same cellular pathways. Furthermore, we demonstrate that the pathway of an uncharacterized gene may be inferred from those of its functionally related partners. Therefore, we are now able to assign most of the genes within bacteria to cellular pathways.

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