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Computational investigation of OH and O states in the catalytic mechanism of cytochrome c oxidase

โœ Scribed by Sharma, V.; Wikstrom, M.


Book ID
123090176
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
69 KB
Volume
1817
Category
Article
ISSN
0005-2728

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## Abstract Cytochrome P450 (CYP) is deeply involved in the metabolism of chemicals including pharmaceuticals. Therefore, polymorphisms of this enzyme have been widely studied to avoid unfavorable side effects of drugs in chemotherapy. In this work, we performed computational analysis of the mechan