Computational Fluid Dynamics Applications in Bio and Biomedical Processes: Biotechnology Applications

✍ Scribed by Satya Eswari Jujjavarapu, Tukendra Kumar, Sharda Gupta

• Publisher: Springer
• Year: 2024
• Tongue: English
• Leaves: 198
• Category: Library

✦ Synopsis

This book covers emerging areas in novel design and their hydrodynamic properties relevant to bioreactors, environmental system, electrochemical systems, food processing and biomedical engineering. This book uses an interdisciplinary approach to provide a comprehensive prospective simulation modeling and hydrodynamic study in advanced biotechnological process and includes reviews of the most recent state of art in modeling and simulation of flows in biological process, such as CFD. Written by internationally recognized researchers in the field, each chapter provides a strong introductory section that is useful to both readers currently in the field and readers interested in learning more about these areas.

✦ Table of Contents

About This Book
Contents
About the Authors
1 Computational Fluid Dynamics: Fundamentals and Applications in the Design and Optimization of Various Bioreactors
1 Introduction
2 Background
3 Computational Fluid Dynamics
3.1 Numerical Method in CFD
3.2 CFD Software and Overview of Modelling
4 Computational Fluid Dynamics for Design and Optimization of Reactors
4.1 Activated Sludge Bioreactors
4.2 Fixed-Bed Reactors
4.3 Membrane Bioreactors
4.4 Trickle-Bed Reactors
4.5 Fluidized Bed Bioreactors
5 Future Prospective
6 Conclusion
References
2 CFD Modelling for Optimization of Wastewater Treatment Processes: Towards a Low-Cost Cleaner Future Tool
1 Introduction
2 Background
3 Optimization of Bioprocess in Wastewater Treatment Plants via a CFD
3.1 Suspended Growth (Flocculent)
3.2 Anaerobic Processes
3.3 Disinfection
4 CFD for Optimization of Wastewater Treatment Plant
4.1 Primary Sedimentation
4.2 Secondary Sedimentation
4.3 Grit Removal
4.4 Dissolved Air Flotation
5 CFD Modelling and Design of Wastewater Treatment Reactor
5.1 Large-Scale Flotation Reactor
5.2 Membrane Reactors
5.3 Activated Sludge Channel Reactor
5.4 Continuous Solar-Collector-Reactors
6 Hydrodynamics and Mass Transfer Simulation for Other Wastewater Reactors
7 Techno-Economic Analysis
8 Future Prospective
9 Conclusion
References
3 An Overview of Computational Fluid Dynamics in Modelling and Simulation of Microbial Fuel Cells
1 Introduction
2 Background
3 CFD Modelling Strategy for MFC Systems
3.1 Assumptions for MFC Modelling
3.2 Models for MFC Modelling
3.3 Model Simulation in CFD for MFC
4 Challenges and Future of CFD for MFC Modelling
4.1 Computational Complexity and Resource Requirements
4.2 CFD Model Validation
5 Conclusion
References
4 Computational Fluid Dynamics in Biomedical Engineering
1 Introduction
2 Background
3 Reconstruction of the System
3.1 Acquisition of Medical Image
4 Image Segmentation
4.1 Edge Detection
4.2 Thresholding-Based Segmentation
4.3 Region-Based Segmentation Technique
4.4 Deep Learning-Based Segmentation
5 Mesh Generation
6 Boundary Condition Generation
7 Applications of CFD in Biomedical Applications
7.1 Cerebral Aneurysm
7.2 Respiratory Tract
7.3 Microfluidics
7.4 Drug Administration
7.5 Simulating Microswimmers
7.6 CFD in Cardiovascular Applications
7.7 Fluid–Structure Interaction to Investigate the Upper Airway of Obstructive Sleep Apnoea (OSA) Patients
7.8 Fluid Dynamics in Syringomyelia Cavities
8 Conclusion
References
5 Computational Fluid Dynamics in the Human Integumentary Systems
1 Introduction
2 Background
3 Anatomy and Physiology of the Integumentary System
4 Mathematical Tools for Skin CFD
4.1 Diffusion Model
4.2 Fluid Flow Model
5 Case Study
5.1 Strain and Stress Study
5.2 Diffusion Study
5.3 Wound Healing Study
5.4 Microneedle Insertion Analysis
6 Conclusion
References
6 Role of Computational Fluid Dynamics in Cancer
1 Introduction
2 Background
3 Fluid Mechanics Study of Cancer
3.1 Hemodynamics Transport Study of Cancer
3.2 Interstitial Fluid Transport Study of Cancer
4 Diagnosis of Cancer Metastasis
5 Pharmacokinetics Study
6 Personalized Treatment for Cancer Study
7 Case Study of CFD to Evaluate the Effectiveness and Precision of Specific Cancer Treatment Methods
7.1 Intra-arterial Chemotherapy
7.2 Radioembolization (RE)
7.3 Intraperitoneal Chemotherapy
7.4 Modelling of Endovascular Chemofilter Device
References
7 Computational Fluid Dynamics for Modelling and Simulation of Drug Delivery
1 Introduction
2 Background
3 Case Study for Drug Delivery Application in CFD
3.1 Respiratory System
3.2 Nervous System
3.3 Ocular System
3.4 Transdermal System
References