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Computational evaluation of pKafor oxygenated side chain containing amino acids interacting with Aluminum

✍ Scribed by J. I. Mujika; J. M. Ugalde; X. Lopez


Book ID
105886559
Publisher
Springer
Year
2010
Tongue
English
Weight
340 KB
Volume
128
Category
Article
ISSN
1432-2234

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A novel type of conformationally restricted peptides with the structure of H-D-Xaa-Phe-NH-CH 2 -C 6 H 5 has been developed as inhibitors of serine proteinase chymotrypsin. The D-Xaa-alkyl and Phe-phenyl groups resulted in a formation of the hydrophobic core due to the side-chain-side-chain CH/ inter