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Computational Characterization of Binding of Small Molecule Inhibitors to HIV-1 gp41

✍ Scribed by Kuizhong Song; Ju Bao; Yueming Sun; John Z. H. Zhang


Book ID
102097007
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
130 KB
Volume
29
Category
Article
ISSN
0256-7660

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We examined the binding of the gp120 envelope glycoprotein (gp120) of the human immunodeficiency virus (HIV-1) to sulfatide (Gals), galactocerebroside (GalC), and GM1-ganglioside (GM1). The gp120 glycoprotein bound to Gals but not to GalC or GM1 by enzyme-linked immunosorbent assay (ELISA) and by an