Computational approaches for combinatorial library design and molecular diversity analysis

✍ Scribed by Jeffrey M Blaney; Eric J Martin

• Publisher: Elsevier Science
• Year: 1997
• Tongue: English
• Weight: 637 KB
• Volume: 1
• Category: Article
• ISSN: 1367-5931
• DOI: 10.1016/s1367-5931(97)80108-1

✦ Synopsis

New approaches for combinatorial library design and molecular diversity analysis have been developed by extending previous work from the fields of quantitative structure-activity relationship, computational chemistry, and chemical information. Recent work has begun to address design efficiency and validation of descriptors for combinatorial library design.