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Computation of molecular weight averages for DNA molecules containing both preformed and randomly induced single-strand breaks

✍ Scribed by Donald M. Crothers; H.-CH. Spatz; Elliot Elson


Publisher
Wiley (John Wiley & Sons)
Year
1969
Tongue
English
Weight
314 KB
Volume
7
Category
Article
ISSN
0006-3525

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✦ Synopsis


We derive equations for calculating the number-, weight-, and z-average lengths between single-strand breaks in DNA molecules. Provision is made for the existence of preformed breaks under genetic control; these are assumed to be fixed in number in each molecule, but may be variable in position. Breaks due to random degradation may be superimposed on the pre-existing breaks. An example is given for illustrative purposes.