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Compressive forces induce osteogenic gene expression in calvarial osteoblasts

โœ Scribed by Bjoern Rath; Jin Nam; Thomas J. Knobloch; John J. Lannutti; Sudha Agarwal

Book ID
108159548
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
874 KB
Volume
41
Category
Article
ISSN
0021-9290

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## Abstract Mechanical loading of bone generates fluid flow within the mineralized matrix that exerts fluid shear stress (FSS) on cells. We examined effects of FSS on receptor activator of nuclear factor ฮบ B ligand (RANKL), a critical factor for osteoclast formation. Primary murine osteoblasts were