Comprehensive Two-Dimensional Gas Chromatography – GC×GC

✍ Scribed by Philip Marriott

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 289 KB
• Volume: 27
• Category: Article
• ISSN: 1615-9306
• DOI: 10.1002/jssc.200490016

✦ Synopsis

Comprehensive Two-Dimensional Gas Chromatography -GC6GC Two-dimensional separations have undergone a significant resurgence in popularity in recent years. The added complexity that a second separation dimension brings to the analytical set-up may or may not present a technical challenge, depending on how the two individual separations are to be hyphenated. It also depends on the nature of the two separation steps, e. g. whether they employ gas, or liquid, or gas/liquid, combination. To justify the move to the coupled-column experiment, there must be some pay-back to the analyst in respect of chromatographic performance. This can be measured in either or both of analytical sensitivity and separation power. Inherent in this is the recognition that a single column analysis must therefore not deliver sufficient power for a particular analysis. This might then seem to call into question many routine analyses employing a single column, especially where solute components overlap.