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Comprehensive Physiology || Clinical and Molecular Genetic Features of Hereditary Pulmonary Arterial Hypertension

✍ Scribed by Terjung, Ronald


Book ID
121813782
Publisher
John Wiley & Sons, Inc.
Year
2011
Weight
686 KB
Category
Article
ISBN
0470650710

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Heterozygous germline mutations of BMPR2 contribute to familial clustering of pulmonary arterial hypertension (PAH). To further explore the genetic basis of PAH in isolated cases, we undertook a candidate gene analysis to identify potentially deleterious variation. Members of the bone morphogenetic