Comprehensive pathway-based interrogation of genetic variations in the nucleotide excision DNA repair pathway and risk of bladder cancer

Genetic polymorphisms in DNA base-excisi

Genetic polymorphisms in DNA base-excision repair genes ADPRT, XRCC1, and APE1 and the risk of squamous cell carcinoma of the head and neck

✍ Chunying Li; Zhibin Hu; Jiachun Lu; Zhensheng Liu; Li-E Wang; Adel K. El-Naggar; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 242 KB 👁 2 views

## Abstract ## BACKGROUND. Tobacco smoke contains numerous carcinogens that cause DNA damage, including oxidative lesions that are removed effectively by the base‐excision repair (BER) pathway, in which adenosine diphosphate ribosyl transferase (ADPRT), x‐ray repair cross‐complementing 1 (XRCC1),