A complex chromosome rearrangement (CCR) with eight breakpoints resulting in four derivative chromosomes (4, 11, 12 and 13) was detected prenatally in a male fetus of a twin pregnancy. The karyotype of the female second fetus was normal. The apparently balanced de novo CCR was identified by classica
β¦ LIBER β¦
Comprehensive cytogenetic analysis including multicolor spectral karyotyping and interphase fluorescence in situ hybridization in lymphoma diagnosis: a summary of 154 cases
β Scribed by Yao-Shan Fan; Kamilia Rizkalla
- Book ID
- 114135542
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 89 KB
- Volume
- 143
- Category
- Article
- ISSN
- 0165-4608
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## Abstract Patients with acute myeloid leukemia (AML) and a complex aberrant karyotype have a poor outcome despite intensive antileukemic treatment. The aim of this study was to analyze in detail the genetic abnormalities in this subgroup of AML. Therefore, 125 AML cases with complex aberrant kary