Array-CGH analysis indicates a high prev
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Claude Bendavid; Lucie Rochard; Christèle Dubourg; Jonathan Seguin; Isabelle Gic
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Article
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2009
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John Wiley and Sons
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English
⚖ 205 KB
Holoprosencephaly (HPE) is the most frequent malformation of the brain. To date, 12 different HPE loci and 8 HPE genes have been identified from recurrent chromosomal rearrangements or from the sequencing of genes from Nodal and SHH pathways. Our cohort of HPE patients presents a high genetic hetero