Comprehensive Analysis of the Substituent Distribution in Hydroxyethyl Celluloses by Quantitative MALDI-ToF-MS

✍ Scribed by Roland Adden; Romy Müller; Gunnar Brinkmalm; Rudolf Ehrler; Petra Mischnick

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 196 KB
• Volume: 6
• Category: Article
• ISSN: 1616-5187
• DOI: 10.1002/mabi.200600028

✦ Synopsis

Abstract

Summary: Three HECs with a high MS (HEC 1: 1.89, HEC 2: 1.94, HEC 3: 3.03) were analyzed with respect to their substituent distribution and tandem reaction in the glucosyl unit by GLC of the corresponding glucitol acetates, and along the polymer chain by MALDI‐ToF‐MS after a multi‐step sample preparation. For comparison of the experimental data with a random pattern an extended Bernoulli plot was applied to calculate a random distribution for the composition of un‐, mono‐, di‐, tri‐, and up to heptasubstituted glucosyl units (c~0~, c~1~, c~2~, … c~7~).
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