Composition of Reductive Cleavage Products of Cyclopenta[d]isoxazolines.
β Scribed by I. P. Antonevich
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 117 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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The preparation of highly substituted J-hydroxy carbonyl compounds from isoxazolines is featured in a synthesis of crispatic acid. A J-hydroxy imine, the proposed intermediate in this transformation, is isolated for the first time and a stereoselective hydroboration of a 5-vinyl substituted isoxazol
## Abstract We report herein the synthesis of new synthons obtained by reductive opening of 3βglycosylβ5βsubstitutedβ2βisoxazolines. Different cleavage products have been obtained depending on the substituents (aliphatic or aromatic) in position five of the heterocycle ring. The new compounds are c