Spectrin is the major protein of the membrane erythrocyte skeleton. More recently, homologous but non-identical spectrins (fodrins) were also found in various non-erythroid tissues. Spectrin mRNA in erythroid and various non-erythroid cells was examined by direct hybridization with human a-spectrin,
Composition and expression of spectrin-based membrane skeletons in non-erythroid cells
β Scribed by Randall T. Moon; Andrew P. McMahon
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 840 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0265-9247
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β¦ Synopsis
Localization of the three phosphorylation sites on each heavy chain of Acanthamoeba myosin 11 to a segment at the end of the tail. J. Bid. Chem. 257,45294534. 14 PAGH, K., MARUTA, H., CLAVIU, M. & GERISCH, G. (1984). Localization of two phosphorylation sites adjacent to a region important for polymerisation on the tail of Dictyostelium myosin. EMBO 1. 3, 3271-3278. 15 KORN, E. D. (1982). Acanthamoeba castellani: methods and perspective for studies of cytoskeletal proteins. Methods Cell Biol. 25 8, 313-332.
18 KUCZMARSKI, E. R. & SPUDICH, J. A. (1980). Regulation of myosin self-assembly : phosphorylation of Dictyostelium heavy chain inhibits formation of thick filaments. Proc. Nut. Acad. Sci. USA 11, 7292-7296.
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## Abstract Combination of multiple mRNA markers has been largely investigated for detection of circulating cancer cells. However, current PCRβbased methods are relatively expensive and time consuming. The aim of this study was to develop a membrane arrayβbased multimarker assay for detection of ci