Comportement d'agressivité intraspécifique induit par l'apomorphine chez le rat

✍ Scribed by B. Senault

• Book ID: 104763832
• Publisher: Springer
• Year: 1970
• Tongue: English
• Weight: 913 KB
• Volume: 18
• Category: Article
• ISSN: 0033-3158
• DOI: 10.1007/bf00412673

✦ Synopsis

Apomorphine (1 mg/kg i.v.) has been found to induce aggressive behaviour in rats. Having studied the influence of several factors viz. auditory stimulus, drug dosage, age, sex, strain, and cage size, an experimental design was adopted. Using this design three populations were distinguished among 1524 pairs of rats studied: a) with no agression behaviour at all; b) with a moderate, short lasting and inconstant one; e) with a severe, long lasting and reproducible one. The aggressive behaviour induced by apomorphine was not correlated with that induced by electrical stimulation nor with that induced by killing mice. Several psychotropic drugs were found to antagonise this action: neuroleptics (except Reserpine), tranquillisers (Chlordiazepoxide, Diazepam, Meprobamate, Hydroxyzine), morphine and atropine.