Complications of anterior cervical discectomy and fusion using recombinant human bone morphogenetic protein-2
โ Scribed by Rahul Vaidya; Julia Carp; Anil Sethi; Stephen Bartol; Joseph Craig; Clifford M. Les
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 279 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0940-6719
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๐ SIMILAR VOLUMES
Recombinant human bone morphogenetic protein-2 (rhBMP-2) is known to induce orthotopic and ectopic bone formation in vivo. Several in vitro studies using rat or mouse clonal cell lines have shown that rhBMP-2 may be involved in the differentiation of osteoblasts from osteoblast precursor cells or st
## Abstract Bone morphogenetic protein (BMP)โ2 plays an important role in bone growth and regeneration; however, BMPโ2 is easily lost by diffusion through body fluid and has some inhibitory pathways. To address this problem, we previously immobilized recombinant human BMPโ2 (rhBMPโ2) on succinylate