Complexity of protein folding
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Aviezri S. Fraenkel
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Article
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1993
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Springer
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English
β 719 KB
It is believed that the native folded three-dimensional conformation of a protein is its lowest free energy state, or one of its lowest. It is shown here that both a two-and three-dimensional mathematical model describing the folding process as a free energy minimization problem is NPhard. This mean