โ Scribed by Y. F. Shafiq; M. A. A. Al-Janabi; M. A. M. Abdel-Azeez
No coin nor oath required. For personal study only.
The oxidation state of technetiumโpyrophosphate (99mโTc PYP) reduced by SnCl~2~.2H~2~ O was determined by radiochromatography. Two different complexes were formed (complex I and complex II). The oxidation states of Tc to be III or IV or both in complex II or hydrated technetium dioxide in complex I were investigated. Formation of Tc (III)/Tc(IV)โPYP and hydrated technetium dioxideโPYP complexes were studied by radiochromatography and by biodistribution in mice. Experiments in animals helped to clarify the behaviour of these complexes. Thus urine obtained from one group of mice injected with 99mโTcโPYP complexes wase reinjected to another group of mice. It was found that complex II excreted in the urine was not broken down while cleavage and deposition of 99mโTcโspecies were found with complex I excreted in urine.
๐ SIMILAR VOLUMES
A series of reactions between the technetium tricarbonyl core, [^99m^Tc(CO)~3~(OH~2~)~3~]^+^ and both the bifunctional chelate dithiazole valeric acid (DTV) and insulin derivatized with DTV were performed using microfluidic, microwave, and conventional labeling methods. At low concentrations of liga