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Complexation of Budesonide in Cyclodextrins and Particle Aerodynamic Characterization of the Complex Solid Form for Dry Powder Inhalation

✍ Scribed by Carla M Vozone; Helena M. Cabral Marques


Book ID
110431363
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
113 KB
Volume
44
Category
Article
ISSN
0923-0750

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Inclusion complexation between celecoxib, a specific cyclooxygenase II inhibitor, and beta-cyclodextrin (b-CD) was studied in solution and solid state. Drug cyclodextrin complexes were prepared by spray drying while physical mixtures were obtained by simple blending. Inclusion complexes were charact