✦ LIBER ✦

Complex repetitive discharges: Cause or effect of neurogenic muscle hypertrophy?

✍ Scribed by Julie Rowin; Matthew N. Meriggioli

Book ID: 101254491
Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 159 KB
Volume: 22
Category: Article
ISSN: 0148-639X
DOI: 10.1002/(sici)1097-4598(199911)22:11<1603::aid-mus20>3.0.co;2-q

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✦ Synopsis

We report a patient with adult-onset spinal muscular atrophy (SMA) of the scapulohumeral type with neurogenic muscle hypertrophy (NMH) in markedly weakened biceps muscles in association with continuous complex repetitive discharges (CRDs). This is an apparently unique case due to the bilaterality of the NMH associated with CRDs as well as the well-circumscribed symmetric upper extremity distribution of the hypertrophy. The possible mechanisms of NMH in association with spontaneous motor activity are discussed.