Complex regulation of prothymosin alpha in mammary tumors arising in transgenic mice
✍ Scribed by Lourdes Loidi; Tomás García-caballero; Anxo Vidal; Juan Zalvide; Rosalía Gallego; Fernando Domínguez
- Book ID
- 117176235
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 632 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0024-3205
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## Abstract ## Purpose To compare T1‐ or T2‐weighted magnetic resonance imaging (MRI) and ultrasonography (US) as tools for in vivo mapping of different tissue components in spontaneous tumors of transgenic mice. ## Materials and Methods Human‐like mammary adenocarcinomas from FVB/neuT transgeni
Transgenic mice carrying the HER-2/neu proto-oncogene under tissue-specific transcriptional control of a mammary tumor virus long terminal repeat (Tg-MMTVneu mice) spontaneously develop mammary carcinomas. HER-2/neu is a tumor antigen that can be recognized by cytotoxic T lymphocytes if tumor cells