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Complex caged polyisoprenylated benzophenone derivatives, sampsoniones A and B, from Hypericum sampsonii

✍ Scribed by Li-Hong Hu; Keng-Yeow Sim

Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 240 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)01741-9

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✦ Synopsis

The aerial parts of the Chinese medicinal plant Hypericum sampsonii yielded two novel metabolites, sampsoniones A and B, which are characterised by their unique tetracyclo-polyketonic core with benzoyl, 3methyl-2-butenyl and geranyl substituents. Their structures were determined by detailed spectral analysis. Sampsonione A exhibited moderate cytotoxicity to P388 cancer cell line.

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