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Complex base-induced generation of 3,4-dehydroquinoline: a new access to quinoline derivatives

✍ Scribed by Stéphanie Blanchard; Gérald Guillaumet; Paul Caubère

Book ID: 104231395
Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 87 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)01339-9

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✦ Synopsis

Dehydroquinoline was easily generated from 3-bromoquinoline and a complex base NaNH 2 -tBuONa. Nucleophilic condensation of amines and thiolates were performed in good yields.

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