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Complete remission of paraneoplastic sensorimotor neuropathy: A case associated with small-cell lung cancer responsive to chemotherapy, plasma exchange, and radiotherapy

✍ Scribed by Dr. David E. Weissman; Jerome L. Gottschall


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
338 KB
Volume
5
Category
Article
ISSN
0733-2459

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✦ Synopsis


A 61-year-old man was found to have small-cell lung cancer following a 1-year history of a progressive peripheral sensorimotor neuropathy . The neuropathy initially improved following chemotherapy, but subsequently progressed to the point of respiratory failure. Treatment with plasma exchange, additional chemotherapy, and radiotherapy resulted in a sustained complete tumor remission and neurologic recovery. The role of plasma exchange is unclear, but its use should be considered in cases of severe sensorimotor neuropathy unresponsive to antineoplastic treatment.