Allogeneic peripheral blood stem cell transplantation from an HLA-identical sibling was performed for a 38-year-old male with refractory acute myeloblastic leukemia. The patient was conditioned with total body irradiation (TBI) and high-dose cytosine arabinoside (Ara-C). G-CSF (300 ยตg/body) was star
โฆ LIBER โฆ
Complete remission in three patients with acute myeloblastic leukemia by administration of G-CSF without antileukemic agents
โ Scribed by Takahashi, Masuhiro; Koike, Tadashi; Aizawa, Yoshifusa; Kashimura, Makoto; Hayatsu, Kunihiro; Nagai, Ko-ichi; Abe, Atsushi; Urushiyama, Masaru; Yagisawa, Kumiko
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 48 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0361-8609
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โฆ Synopsis
We describe 3 patients with acute myeloblastic leukemia (AML), who received rhG-CSF for infections such as pneumonia or for prophylaxis of infection, and who achieved complete remission. They had not received any antileukemic therapy before or during the administration of rhG-CSF. These findings suggest the possibility that complete remission can be brought about by G-CSF itself in some patients with AML. Am.
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John Wiley and Sons
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โ 115 KB
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