Complete Relaxation and Conformational Exchange Matrix Analysis of STD-NMR Spectra of Ligand Receptor Complexes

Complete Relaxation and Conformational E

Complete Relaxation and Conformational Exchange Matrix (CORCEMA) Analysis of Intermolecular Saturation Transfer Effects in Reversibly Forming Ligand–Receptor Complexes

✍ V. Jayalakshmi; N.Rama Krishna 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 296 KB

A couple of recent applications of intermolecular NOE (INOE) experiments as applied to biomolecular systems involve the (i) saturation transfer difference NMR (STD-NMR) method and (ii) the intermolecular cross-saturation NMR (ICS-NMR) experiment. STD-NMR is a promising tool for rapid screening of a