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Complete protection of sodium valproate from humidity by using a hydrotalcite composite

✍ Scribed by Hirokazu Nakayama; Hiroko Akasaka; Mitsutomo Tsuhako


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
124 KB
Volume
98
Category
Article
ISSN
0022-3549

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✦ Synopsis


Complete protection of sodium valproate from humidity was successfully accomplished by intercalation into a hydrotalcite-like compound. The obtained hybrid of sodium valproate and the hydrotalcite-like compound was stable and not at all hygroscopic. Even under a relative humidity of 97%, the adsorbed amount of water was less than 0.5%.